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Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 3.034

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_102553343	13.670	NM_001031692 NM_005824	LRRC17	leucine rich repeat containing 17
chr7_+_116165089	10.156		CAV1	caveolin 1, caveolae protein, 22kDa
chr7_+_116165043	10.078	NM_001172895	CAV1	caveolin 1, caveolae protein, 22kDa
chr7_+_116164838	9.608	NM_001753	CAV1	caveolin 1, caveolae protein, 22kDa
chr12_+_13349601	8.199	NM_001423	EMP1	epithelial membrane protein 1
chr12_-_56106061	7.993	NM_001144997	ITGA7	integrin, alpha 7
chr12_+_13349720	7.834		EMP1	epithelial membrane protein 1
chr9_+_139872014	7.345		PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr1_-_173174611	7.187		TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr8_-_42065037	6.978		PLAT	plasminogen activator, tissue
chr14_+_85996454	6.913	NM_013231	FLRT2	fibronectin leucine rich transmembrane protein 2
chr8_-_42065193	6.708	NM_000930 NM_033011	PLAT	plasminogen activator, tissue
chr21_+_46875402	6.539	NM_030582	COL18A1	collagen, type XVIII, alpha 1
chr16_+_70502824	6.515		FUK	fucokinase
chr15_-_35087748	6.232	NM_005159	ACTC1	actin, alpha, cardiac muscle 1
chrX_+_99899162	6.154	NM_014467	SRPX2	sushi-repeat containing protein, X-linked 2
chr2_-_218843541	5.968		TNS1	tensin 1
chr9_+_139871954	5.280	NM_000954	PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr17_-_76921453	4.856	NM_003255	TIMP2	TIMP metallopeptidase inhibitor 2
chr10_+_17271341	4.849		VIM	vimentin
chr10_+_17271302	4.793		VIM	vimentin
chr17_-_76921205	4.695		TIMP2	TIMP metallopeptidase inhibitor 2
chr11_+_114166534	4.671	NM_006169	NNMT	nicotinamide N-methyltransferase
chr17_-_76975932	4.669	NM_005567	LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein
chr10_+_17271277	4.660		VIM	vimentin
chr9_+_116356407	4.659		RGS3	regulator of G-protein signaling 3
chr10_+_17271276	4.554		VIM	vimentin
chrX_+_102631408	4.492		NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr12_+_119616594	4.445	NM_014365	HSPB8	heat shock 22kDa protein 8
chr5_-_111093030	4.385	NM_001142482 NM_001142481	C5orf13	chromosome 5 open reading frame 13
chrX_+_102631267	4.352	NM_206915 NM_206917	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr14_+_85996512	4.330		FLRT2	fibronectin leucine rich transmembrane protein 2
chr1_+_151512760	4.315	NM_001126337 NM_020127	TUFT1	tuftelin 1
chr3_+_8775485	4.289	NM_001234 NM_033337	CAV3	caveolin 3
chr9_+_124086842	4.234		GSN	gelsolin
chr17_+_38599651	4.217	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr5_-_111092918	4.108	NM_004772	C5orf13	chromosome 5 open reading frame 13
chr2_-_217560247	4.098	NM_000599	IGFBP5	insulin-like growth factor binding protein 5
chr9_+_116356199	4.091	NM_144489	RGS3	regulator of G-protein signaling 3
chr5_-_111093251	4.088	NM_001142479 NM_001142480 NM_001142478	C5orf13	chromosome 5 open reading frame 13
chr8_-_18541441	4.056		PSD3	pleckstrin and Sec7 domain containing 3
chr11_-_6341708	4.042	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chr20_+_9049660	3.966	NM_001172646	PLCB4	phospholipase C, beta 4
chr9_-_130617009	3.952	NM_000118 NM_001114753	ENG	endoglin
chr9_-_13279562	3.951		MPDZ	multiple PDZ domain protein
chr17_-_76921076	3.910		TIMP2	TIMP metallopeptidase inhibitor 2
chr5_-_111092865	3.900		C5orf13	chromosome 5 open reading frame 13
chr1_-_153600714	3.866	NM_005979	S100A13	S100 calcium binding protein A13
chr9_-_130616957	3.842		ENG	endoglin
chr9_-_79520878	3.685	NM_015225	PRUNE2	prune homolog 2 (Drosophila)
chr21_-_28217692	3.652	NM_006988	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chrX_+_99899388	3.646		SRPX2	sushi-repeat containing protein, X-linked 2
chr1_-_153599969	3.639	NM_001024211	S100A13	S100 calcium binding protein A13
chr15_-_90347534	3.580		ANPEP	alanyl (membrane) aminopeptidase
chr7_+_100770378	3.547	NM_000602 NM_001165413	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr1_+_203595897	3.536	NM_001001396 NM_001684	ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr7_+_143078608	3.500		ZYX	zyxin
chr7_+_143079354	3.428		ZYX	zyxin
chr9_-_130616760	3.404		ENG	endoglin
chr2_-_192711923	3.321	NM_004657	SDPR	serum deprivation response
chr12_+_66218141	3.317	NM_003483 NM_003484	HMGA2	high mobility group AT-hook 2
chr1_+_203595929	3.286		ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr10_+_17270469	3.246		VIM	vimentin
chr12_-_54812936	3.184		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr21_-_28217272	3.178		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr2_-_192711651	3.085		SDPR	serum deprivation response
chr11_-_2159472	3.036		IGF2	insulin-like growth factor 2 (somatomedin A)
chr7_+_22767101	3.032		IL6	interleukin 6 (interferon, beta 2)
chr21_+_47531369	2.940		COL6A2	collagen, type VI, alpha 2
chr2_-_37899227	2.917	NM_006449	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr9_+_124043719	2.886		GSN	gelsolin
chr12_-_54813002	2.810		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chrX_-_13956530	2.774		GPM6B	glycoprotein M6B
chr3_-_32022734	2.766		OSBPL10	oxysterol binding protein-like 10
chr17_-_15164043	2.749	NM_153322	PMP22	peripheral myelin protein 22
chr10_+_17271859	2.683		VIM	vimentin
chr6_+_132129195	2.673		ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr10_+_124320180	2.660	NM_004406 NM_007329 NM_017579	DMBT1	deleted in malignant brain tumors 1
chr17_+_4854383	2.660	NM_001193503 NM_001976 NM_053013	ENO3	enolase 3 (beta, muscle)
chr1_-_153538305	2.649	NM_005978	S100A2	S100 calcium binding protein A2
chr9_-_130616592	2.642		ENG	endoglin
chr1_-_153599743	2.616	NM_001024212	S100A13	S100 calcium binding protein A13
chr8_-_12973752	2.567	NM_001164271	DLC1	deleted in liver cancer 1
chr7_+_22766765	2.497	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chrX_-_154688260	2.478	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chr1_-_201342318	2.475		TNNT2	troponin T type 2 (cardiac)
chr2_-_24307529	2.465	NM_004881 NM_147184	TP53I3	tumor protein p53 inducible protein 3
chr7_-_151574209	2.432	NM_016203	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr20_+_44519590	2.415	NM_000308 NM_001127695 NM_001167594	CTSA	cathepsin A
chr5_-_73937248	2.408	NM_003633	ENC1	ectodermal-neural cortex 1 (with BTB-like domain)
chr3_-_52488030	2.388	NM_003280	TNNC1	troponin C type 1 (slow)
chr10_+_17271956	2.382		VIM	vimentin
chr1_-_243418675	2.362	NM_001042404 NM_001042405 NM_014812	CEP170	centrosomal protein 170kDa
chr15_-_77363122	2.360		TSPAN3	tetraspanin 3
chr11_-_65326129	2.265		LTBP3	latent transforming growth factor beta binding protein 3
chr8_-_13134028	2.231		DLC1	deleted in liver cancer 1
chr15_-_90347173	2.202		ANPEP	alanyl (membrane) aminopeptidase
chr12_-_8815370	2.185	NM_003480	MFAP5	microfibrillar associated protein 5
chrX_+_154114609	2.171	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chrX_+_154611748	2.131	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chr12_-_8815479	2.120		MFAP5	microfibrillar associated protein 5
chr13_+_98795468	2.106		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr2_-_37898768	2.088		CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr6_-_46922533	2.062	NM_015234	GPR116	G protein-coupled receptor 116
chr20_+_33759773	2.061	NM_006404	PROCR	protein C receptor, endothelial
chr3_-_32023237	2.013	NM_001174060 NM_017784	OSBPL10	oxysterol binding protein-like 10
chr15_-_40213087	2.007	NM_007223	GPR176	G protein-coupled receptor 176
chr15_-_90358057	2.001	NM_001150	ANPEP	alanyl (membrane) aminopeptidase
chr2_-_216300444	1.957		FN1	fibronectin 1
chr3_-_149421059	1.955	NM_001168278	WWTR1	WW domain containing transcription regulator 1
chr9_-_23821808	1.919		ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr20_+_19867075	1.910	NM_001242581	RIN2	Ras and Rab interactor 2
chr5_-_172198160	1.907	NM_004417	DUSP1	dual specificity phosphatase 1
chr22_-_39640956	1.833	NM_002608	PDGFB	platelet-derived growth factor beta polypeptide
chr9_+_124030455	1.833		GSN	gelsolin
chr2_+_66662692	1.796		MEIS1	Meis homeobox 1
chr9_-_113800243	1.766	NM_001401 NM_057159	LPAR1	lysophosphatidic acid receptor 1
chr5_-_16936371	1.763	NM_012334	MYO10	myosin X
chr1_-_22263676	1.761	NM_005529	HSPG2	heparan sulfate proteoglycan 2
chr6_+_132129154	1.757	NM_006208	ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr2_+_109237679	1.716	NM_001193484	LIMS1	LIM and senescent cell antigen-like domains 1
chr16_-_28550324	1.705	NM_001042483 NM_012385	NUPR1	nuclear protein, transcriptional regulator, 1
chr22_+_33196801	1.697	NM_000362	TIMP3	TIMP metallopeptidase inhibitor 3
chr12_-_8815266	1.696		MFAP5	microfibrillar associated protein 5
chr5_-_54281345	1.655	NM_001135604 NM_007036	ESM1	endothelial cell-specific molecule 1
chr10_-_128077072	1.596	NM_003474 NM_021641	ADAM12	ADAM metallopeptidase domain 12
chr12_-_54813010	1.587	NM_002205	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_+_203596222	1.554		ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr6_+_39760772	1.545	NM_015345	DAAM2	dishevelled associated activator of morphogenesis 2
chr11_+_32112414	1.526	NM_002901	RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr8_-_82395401	1.520	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr7_+_116166346	1.508	NM_001172896 NM_001172897	CAV1	caveolin 1, caveolae protein, 22kDa
chrX_-_13956445	1.484
chr12_-_56122124	1.482		CD63	CD63 molecule
chr13_+_98795410	1.477	NM_001001715 NM_005766	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_+_162602308	1.466		DDR2	discoidin domain receptor tyrosine kinase 2
chr17_+_27370155	1.461		PIPOX	pipecolic acid oxidase
chr16_+_57662301	1.438	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr15_-_59665053	1.407		MYO1E	myosin IE
chr9_-_23821842	1.387	NM_001171195	ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chrX_-_13956644	1.387	NM_001001994	GPM6B	glycoprotein M6B
chr13_-_96705565	1.386	NM_020121	UGGT2	UDP-glucose glycoprotein glucosyltransferase 2
chr1_-_229569839	1.380	NM_001100	ACTA1	actin, alpha 1, skeletal muscle
chr3_-_149095458	1.336		TM4SF1	transmembrane 4 L six family member 1
chr20_-_60942300	1.332	NM_005560	LAMA5	laminin, alpha 5
chr2_+_66662516	1.307	NM_002398	MEIS1	Meis homeobox 1
chrX_+_149613719	1.303	NM_001177466 NM_005491	MAMLD1	mastermind-like domain containing 1
chr8_+_55370494	1.297	NM_022454	SOX17	SRY (sex determining region Y)-box 17
chr5_+_150020201	1.269	NM_001109974 NM_007286	SYNPO	synaptopodin
chr15_-_90349819	1.245		ANPEP	alanyl (membrane) aminopeptidase
chr14_+_24867926	1.224	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr22_+_30792929	1.224	NM_001204204 NM_012429 NM_033382	SEC14L2	SEC14-like 2 (S. cerevisiae)
chr7_+_75932865	1.210		HSPB1	heat shock 27kDa protein 1
chr10_+_104503724	1.206	NM_001083913	C10orf26	chromosome 10 open reading frame 26
chr1_-_20812727	1.185	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr17_+_57642885	1.184	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr2_-_73316782	1.169		RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr1_+_162602198	1.161	NM_001014796 NM_006182	DDR2	discoidin domain receptor tyrosine kinase 2
chr19_+_50936159	1.147	NM_004533	MYBPC2	myosin binding protein C, fast type
chr2_+_241375030	1.138	NM_002081	GPC1	glypican 1
chr8_+_22022644	1.137	NM_001199 NM_006129	BMP1	bone morphogenetic protein 1
chr19_+_16178170	1.135	NM_001145160	TPM4	tropomyosin 4
chr8_-_62626929	1.096		ASPH	aspartate beta-hydroxylase
chr1_+_101185195	1.071	NM_001078 NM_001199834 NM_080682	VCAM1	vascular cell adhesion molecule 1
chr19_+_41284068	1.040	NM_016154	RAB4B	RAB4B, member RAS oncogene family
chr16_-_19896105	1.028	NM_016235	GPRC5B	G protein-coupled receptor, family C, group 5, member B
chr3_-_50360109	1.024	NM_003773 NM_033158	HYAL2	hyaluronoglucosaminidase 2
chr13_+_113622758	1.008		MCF2L	MCF.2 cell line derived transforming sequence-like
chr4_+_124320664	1.004	NM_005841	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr9_-_113800980	0.992		LPAR1	lysophosphatidic acid receptor 1
chr8_+_22022677	0.991		BMP1	bone morphogenetic protein 1
chr7_+_75932992	0.938		HSPB1	heat shock 27kDa protein 1
chr14_-_50999178	0.934	NM_006575 NM_198794	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5
chr9_+_124030370	0.930	NM_001127662 NM_001127663 NM_001127664 NM_001127665 NM_001127666 NM_001127667 NM_198252	GSN	gelsolin
chr11_+_67777788	0.928	NM_000694 NM_001030010	ALDH3B1	aldehyde dehydrogenase 3 family, member B1
chr7_-_81399286	0.923	NM_000601 NM_001010931 NM_001010932 NM_001010933 NM_001010934	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_-_115300615	0.921	NM_001007553 NM_001130523 NM_001242891 NM_001242892 NM_001242893 NM_007158	CSDE1	cold shock domain containing E1, RNA-binding
chr12_+_57522247	0.917	NM_002332	LRP1	low density lipoprotein receptor-related protein 1
chr2_-_47142939	0.901		MCFD2	multiple coagulation factor deficiency 2
chr7_-_5569200	0.896		ACTB	actin, beta
chr10_+_75673346	0.895		PLAU	plasminogen activator, urokinase
chr22_-_24640850	0.893	NM_001099781 NM_001099782 NM_004121	GGT5	gamma-glutamyltransferase 5
chr8_-_62602285	0.876	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr1_-_115300601	0.874		CSDE1	cold shock domain containing E1, RNA-binding
chr8_+_22022872	0.865		BMP1	bone morphogenetic protein 1
chr1_-_115300583	0.836		CSDE1	cold shock domain containing E1, RNA-binding
chr10_-_128077011	0.835		ADAM12	ADAM metallopeptidase domain 12
chr1_-_23886284	0.828	NM_002167	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr6_+_146864965	0.815		RAB32	RAB32, member RAS oncogene family
chr5_+_140864626	0.809	NM_018928 NM_032406	PCDHGC4	protocadherin gamma subfamily C, 4
chr2_+_10443020	0.796	NM_002149	HPCAL1	hippocalcin-like 1
chr9_+_124030413	0.790		GSN	gelsolin
chr15_-_59665069	0.780	NM_004998	MYO1E	myosin IE
chr4_-_40936640	0.778		APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2
chr12_-_6665220	0.776	NM_001039670 NM_001193457 NM_080730	IFFO1	intermediate filament family orphan 1
chr1_+_64059479	0.762	NM_001172819	PGM1	phosphoglucomutase 1
chr11_-_65325632	0.761	NM_001130144 NM_001164266 NM_021070	LTBP3	latent transforming growth factor beta binding protein 3
chr9_-_132515290	0.756	NM_004878	PTGES	prostaglandin E synthase
chr10_-_126107454	0.751		OAT	ornithine aminotransferase
chr2_-_216300770	0.751	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
3.03	3.52e-06	GO:0009653	anatomical structure morphogenesis
2.16	1.07e-05	GO:0048856	anatomical structure development
1.98	3.34e-05	GO:0032502	developmental process
10.09	1.78e-04	GO:0006469	negative regulation of protein kinase activity
15.24	2.46e-04	GO:0030048	actin filament-based movement
9.52	2.96e-04	GO:0033673	negative regulation of kinase activity
8.92	5.15e-04	GO:0051348	negative regulation of transferase activity
4.57	6.09e-04	GO:0048646	anatomical structure formation involved in morphogenesis
18.00	6.52e-04	GO:0030049	muscle filament sliding
18.00	6.52e-04	GO:0033275	actin-myosin filament sliding
17.53	7.68e-04	GO:0070252	actin-mediated cell contraction
2.04	1.03e-03	GO:0048731	system development
3.33	1.19e-03	GO:0009888	tissue development
4.21	1.69e-03	GO:0072358	cardiovascular system development
4.21	1.69e-03	GO:0072359	circulatory system development
1.89	2.11e-03	GO:0007275	multicellular organismal development
1.67	2.47e-03	GO:0032501	multicellular organismal process
3.36	3.74e-03	GO:0007155	cell adhesion
3.36	3.74e-03	GO:0022610	biological adhesion
6.85	4.72e-03	GO:0001525	angiogenesis
5.27	5.32e-03	GO:0001568	blood vessel development
5.82	6.01e-03	GO:0048514	blood vessel morphogenesis
2.18	1.02e-02	GO:0048869	cellular developmental process
4.91	1.04e-02	GO:0001944	vasculature development
2.16	1.66e-02	GO:0030154	cell differentiation
2.18	2.07e-02	GO:0048583	regulation of response to stimulus
4.57	4.80e-02	GO:0030029	actin filament-based process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
3.32	7.23e-06	GO:0044421	extracellular region part
2.58	1.62e-05	GO:0005576	extracellular region
3.35	1.76e-04	GO:0005615	extracellular space
5.44	2.27e-04	GO:0005578	proteinaceous extracellular matrix
4.88	2.77e-04	GO:0031012	extracellular matrix
5.15	4.05e-04	GO:0015629	actin cytoskeleton
4.45	7.72e-04	GO:0009986	cell surface
7.93	3.39e-03	GO:0044420	extracellular matrix part
7.75	1.50e-02	GO:0030017	sarcomere
9.57	2.12e-02	GO:0005604	basement membrane
13.88	2.34e-02	GO:0042641	actomyosin
25.61	2.45e-02	GO:0005865	striated muscle thin filament
6.60	3.64e-02	GO:0044449	contractile fiber part
6.41	4.27e-02	GO:0030016	myofibril
2.15	4.98e-02	GO:0005856	cytoskeleton

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
3.77	9.55e-04	GO:0008092	cytoskeletal protein binding
4.39	9.70e-03	GO:0032403	protein complex binding
4.10	1.71e-02	GO:0003779	actin binding
3.08	1.75e-02	GO:0005198	structural molecule activity
6.60	3.24e-02	GO:0019838	growth factor binding
8.17	4.00e-02	GO:0005201	extracellular matrix structural constituent
1.33	4.45e-02	GO:0005515	protein binding